Genetics of nicotinic acetylcholine receptors: Relevance to nicotine addiction.

@article{Mineur2008GeneticsON,
  title={Genetics of nicotinic acetylcholine receptors: Relevance to nicotine addiction.},
  author={Yann S. Mineur and Marina R. Picciotto},
  journal={Biochemical pharmacology},
  year={2008},
  volume={75 1},
  pages={323-33}
}
Human twin studies have suggested that there is a substantial genetic component underlying nicotine dependence, ongoing smoking and ability to quit. Similarly, animal studies have identified a number of genes and gene products that are critical for behaviors related to nicotine addiction. Classical genetic approaches, gene association studies and genetic engineering techniques have been used to identify the gene products involved in nicotine dependence. One class of genes involved in nicotine… CONTINUE READING