Genetics of natural resistance to salmonellae in mice.

  title={Genetics of natural resistance to salmonellae in mice.},
  author={Carlos E Hormaeche},
  volume={37 2},
The genetics of natural resistance to salmonellae were studied in F1 hybrid and backcross mice. Overall resistance to Salmonella typhimurium C5 is complex, but one parameter, the early net growth rate of the organism in vivo, is controlled by a single autosomal gene or cluster of genes. 'Slow' net growth rate is necessary but insufficient, for resistance to S. typhimurium C5. Resistance requires the participation of other mechanisms, detectable by the end of the first week, which presumably… CONTINUE READING

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