Genetics of multiple sclerosis.

@article{Oksenberg2005GeneticsOM,
  title={Genetics of multiple sclerosis.},
  author={Jorge R. Oksenberg and Stephen L. Hauser},
  journal={Neurologic clinics},
  year={2005},
  volume={23 1},
  pages={
          61-75, vi
        }
}
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Genetics of Multiple Sclerosis

The genome-wide association studies in MS in large populations in combination with expression quantitative loci (eQTL) and a better understanding of the functional elements in the human genome have promoted a deeper knowledge of MS genetics in the last 10 years, but the genetic implication in the disease is still far from understanding.

Multiple sclerosis: could it be an epigenetic disease?

NOS2A as a candidate gene in Relapsing–Remitting Multiple Sclerosis: A haplotype study using selected subsets of single nucleotide polymorphisms

IFIH1-GCA-KCNH7 locus is not associated with genetic susceptibility to multiple sclerosis in French patients

The two most significant IFIH1 single nucleotide polymorphisms, rs1990760 and rs2068330, reported as involved in MS susceptibility, were genotyped in 591 French Caucasian MS trio families and analyzed using the transmission/disequilibrium test.

Preliminary evidences of a NOS2A protective effect from Relapsing–Remitting Multiple Sclerosis

Research Article Awareness rate of Ardabil city people about multiple sclerosis

Results showed that the knowledge rate of people about MS was in moderate and lower levels, so, present educational programs and increasing knowledge rate about MS by TV and radio programs is necessary.

ROLES OF FAS IN NEURAL PROGENITOR CELL DIFFERENTIATION, SURVIVAL, AND IMMUNE-CELL INTERACTIONS

The studies suggest the Fas system plays multifaceted roles in NPCs and that its exact functions are dependent on both functional Fas expression and presence or absence of FasL, and the main mechanism through which NPCs produce beneficial results in EAE is via peripheral immunoregulation, which is not dependent on Fas expression.

Characterization of D6S2806 and D6S2879 short tandem repeat loci in HLA-DRB1 region in Iranian population.

The D6S2806 locus could be suggested as a marker for linkage analysis and disease-susceptibility investigations in the MHC-DRB1 gene region.

Tumefactive multiple sclerosis: an uncommon diagnostic challenge.

Autologous hematopoietic cell transplantation for multiple sclerosis: a systematic review

Patients with secondary progressive MS refractory to conventional medical treatment have longer progression-free survival following autologous stem cell transplantation with intermediate-intensity conditioning regimens than with high-intensity Conditioning regimens.

References

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Multiple sclerosis: Genomic rewards

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