Genetics of multiple sclerosis

  title={Genetics of multiple sclerosis},
  author={D. Dyment and G. Ebers and A. Sadovnick},
  journal={The Lancet Neurology},
  • D. Dyment, G. Ebers, A. Sadovnick
  • Published 2004
  • Biology, Medicine
  • The Lancet Neurology
  • Multiple sclerosis (MS) is a common demyelinating disease of the central nervous system affecting primarily young adults. Evidence from genetic epidemiological studies demonstrate that the observed familial clustering of MS is primarily due to shared genes between family members. Molecular investigations have failed to elucidate susceptibilty loci with the exception of the HLA DRB1*1501, DQA1*0102, DQB1*0602 haplotype of the major histocompatibility complex. Results from genomic screens stress… CONTINUE READING
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