Genetics of lipoprotein abnormalities associated with coronary artery disease susceptibility.

@article{Breslow2000GeneticsOL,
  title={Genetics of lipoprotein abnormalities associated with coronary artery disease susceptibility.},
  author={Jan L. Breslow},
  journal={Annual review of genetics},
  year={2000},
  volume={34},
  pages={233-254}
}
Coronary heart disease is a complex genetic disease with many genes involved, environmental influences, and important gene-environment interactions. This review discusses the genetic basis of the principal lipoprotein abnormalities associated with coronary heart disease susceptibility in the general population. Individual sections discuss genes regulating LDL cholesterol, HDL cholesterol, and triglyceride levels. A section is included on the effects of the common apo E genetic variation on… CONTINUE READING