Genetics of bipolar disorder: successful start to a long journey.

@article{Craddock2009GeneticsOB,
  title={Genetics of bipolar disorder: successful start to a long journey.},
  author={Nick Craddock and Pamela Sklar},
  journal={Trends in genetics : TIG},
  year={2009},
  volume={25 2},
  pages={
          99-105
        }
}
Family and twin studies attest to the importance of genetic factors influencing susceptibility to bipolar disorder and to its genetic and phenotypic complexity. Although linkage and candidate gene association studies have repeatedly implicated some chromosome regions and certain genes, they have not produced the level of unambiguous support required to confirm the involvement of any specific gene or sequence variant in the pathogenesis of bipolar disorder. However, strong associations have… CONTINUE READING
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