Genetics of basal cell carcinoma.

@article{Zwaan2010GeneticsOB,
  title={Genetics of basal cell carcinoma.},
  author={Sally E de Zwaan and Nikolas K. Haass},
  journal={The Australasian journal of dermatology},
  year={2010},
  volume={51 2},
  pages={81-92; quiz 93-4}
}
Basal cell carcinoma is the most common human malignancy in populations of European origin, and Australia has the highest incidence of basal cell carcinoma in the world. Great advances in the understanding of the genetics of this cancer have occurred in recent years. Mutations of the patched 1 gene (PTCH1) lead to basal cell carcinoma predisposition in Gorlin syndrome. PTCH1 is part of the hedgehog signalling pathway, and derangements within this pathway are now known to be important in the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

"PTCH"-ing it together: a basal cell nevus syndrome review.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] • 2013
View 17 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 166 references

Similar Papers

Loading similar papers…