Genetics of autoimmune diseases.

  title={Genetics of autoimmune diseases.},
  author={Frederick W Miller},
  journal={Experimental and clinical immunogenetics},
  volume={12 3},
Many lines of evidence suggest that autoimmune diseases are the result of chronic immune activation in genetically susceptible individuals following specific environmental exposures. Although the rarity and heterogeneity of autoimmune diseases and the lack of understanding of pathogenetic mechanisms have inhibited progress in the field, genes encoding histocompatibility molecules, immunoglobulins, complement components, peptide transporter proteins, T-cell receptors, sex hormones, cytokines… CONTINUE READING