Genetics of autoimmune diabetes in animal models.

@article{Mcduffie1998GeneticsOA,
  title={Genetics of autoimmune diabetes in animal models.},
  author={Marcia Mcduffie},
  journal={Current opinion in immunology},
  year={1998},
  volume={10 6},
  pages={704-9}
}
Type I diabetes has resisted direct genetic analysis in humans but two excellent models of disease in rodents provide a more readily manipulated alternative for study. These rodent models are being used successfully to localize the genes that are involved in disease pathogenesis in preparation for positional cloning. In addition, mice carrying transgenes… CONTINUE READING