Genetics of austim: complex aetiology for a heterogeneous disorder

@article{Folstein2001GeneticsOA,
  title={Genetics of austim: complex aetiology for a heterogeneous disorder},
  author={S. Folstein and B. Rosen-Sheidley},
  journal={Nature Reviews Genetics},
  year={2001},
  volume={2},
  pages={943-955}
}
  • S. Folstein, B. Rosen-Sheidley
  • Published 2001
  • Biology, Medicine
  • Nature Reviews Genetics
  • Since autism was first recognized as a disorder in 1943, speculation about its aetiology has ranged from biological to psychological and back again. After twin studies during the 1970s and 1980s yielded unequivocal evidence for a genetic component, aetiological research in autism began to focus primarily on uncovering the genetic mechanisms involved. The identification of chromosomal abnormalities and Mendelian syndromes among individuals with autism, in conjunction with data from genome… CONTINUE READING
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    References

    SHOWING 1-10 OF 169 REFERENCES
    Autism: Familial aggregation and genetic implications
    • 197
    Genetic Counseling in Autism and Pervasive Developmental Disorders
    • E. Simonoff
    • Medicine, Psychology
    • Journal of autism and developmental disorders
    • 1998
    • 87
    Genetic studies in autistic disorder and chromosome 15
    • 99
    Autism as a strongly genetic disorder: evidence from a British twin study.
    • 2,292
    Early environmental factors in autism
    • 76
    The neurobiology of autism.
    • 323
    Chromosomal Disorders and Autism
    • C. Gillberg
    • Medicine, Psychology
    • Journal of autism and developmental disorders
    • 1998
    • 238
    Autism and maternally derived aberrations of chromosome 15q.
    • 357
    • PDF
    Chromosome 7q: where autism meets language disorder?
    • 100
    Evidence for a susceptibility gene for autism on chromosome 2 and for genetic heterogeneity.
    • 327