Genetics of Synucleinopathies.

@article{Nussbaum2018GeneticsOS,
  title={Genetics of Synucleinopathies.},
  author={Robert L Nussbaum},
  journal={Cold Spring Harbor perspectives in medicine},
  year={2018},
  volume={8 6}
}
Parkinson's disease (PD), diffuse Lewy body disease (DLBD), and multiple system atrophy (MSA) constitute the three major neurodegenerative disorders referred to as synucleinopathies because both genetic and pathological results implicate the α-synuclein protein in their pathogenesis. PD and DLBD are recognized as closely related diseases with substantial clinical and pathological overlap. MSA, on the other hand, has a distinctive clinical presentation and neuropathological profile. In this… CONTINUE READING

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