Genetics of Sleep and Sleep Disorders

@article{Sehgal2011GeneticsOS,
  title={Genetics of Sleep and Sleep Disorders},
  author={Amita Sehgal and Emmanuel Mignot},
  journal={Cell},
  year={2011},
  volume={146},
  pages={194-207}
}
Sleep remains one of the least understood phenomena in biology--even its role in synaptic plasticity remains debatable. Since sleep was recognized to be regulated genetically, intense research has launched on two fronts: the development of model organisms for deciphering the molecular mechanisms of sleep and attempts to identify genetic underpinnings of human sleep disorders. In this Review, we describe how unbiased, high-throughput screens in model organisms are uncovering sleep regulatory… CONTINUE READING
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