Genetics of Parkinson's disease

  title={Genetics of Parkinson's disease},
  author={Thomas Gasser},
  booktitle={Dialogues in clinical neuroscience},
  • Thomas Gasser
  • Published 2004 in Dialogues in clinical neuroscience
The etiology of most cases of Parkinson's disease (PD) remains unknown. In recent years, however, research has successfully focused on genetic factors contributing to the degeneration of dopaminergic neurons. Causative mutations have been identified in several monogenically inherited forms of the disease. Although these genetic forms of PD are usually rare, the gene discoveries are likely to identify molecular pathways that are also relevant in the sporadic disorder. These studies have led to… CONTINUE READING


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Parkin and its role in Parkinson's disease

  • T. Gasser
  • 2004

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