Genetics of Coronary Artery Disease.

  title={Genetics of Coronary Artery Disease.},
  author={Ruth Mcpherson and Anne Tybjaerg-Hansen},
  journal={Circulation research},
  volume={118 4},
Genetic factors contribute importantly to the risk of coronary artery disease (CAD), and in the past decade, there has been major progress in this area. The tools applied include genome-wide association studies encompassing >200,000 individuals complemented by bioinformatic approaches, including 1000 Genomes imputation, expression quantitative trait locus analyses, and interrogation of Encyclopedia of DNA Elements, Roadmap, and other data sets. close to 60 common SNPs (minor allele frequency>0… CONTINUE READING
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