Genetics of CHD in 2016: Common and rare genetic variants and risk of CHD

  title={Genetics of CHD in 2016: Common and rare genetic variants and risk of CHD},
  author={Daniel I Swerdlow and Steve E. Humphries},
  journal={Nature Reviews Cardiology},
Much of the progress in cardiovascular genetics in 2016 has been driven by next-generation sequencing studies, and the clinical utility of knowing an individual's genotype for predicting their risk of cardiovascular disease is gaining credibility, both for monogenic and polygenic disorders. Additionally, phenotype data are increasingly abundant, although databases linking genotype with clinically relevant phenotypes require optimization. 

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