Genetics of Alcoholic Liver Disease.

  title={Genetics of Alcoholic Liver Disease.},
  author={Quentin M Anstee and Ann K Daly and Christopher Paul Day},
  journal={Seminars in liver disease},
  volume={35 4},
Excess alcohol consumption with consequent alcoholic liver disease (ALD) is a common cause of liver dysfunction and liver-related mortality worldwide. However, although the majority of heavy drinkers will develop steatosis, only a minority progress to advanced liver disease and cirrhosis. Thus, ALD is a complex disease where subtle interpatient genetic variations and environmental factors interact to determine disease progression. One genome-wide association study specifically addressing… CONTINUE READING
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