Genetics and ischaemic stroke.

  title={Genetics and ischaemic stroke.},
  author={Ahamad Hassan and Hugh S. Markus},
  journal={Brain : a journal of neurology},
  volume={123 ( Pt 9)},
Ischaemic stroke can be caused by a number of monogenic disorders, and in such cases stroke is frequently part of a multisystem disorder. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL), due to mutations in the NOTCH: 3 gene, is increasingly appreciated as a cause of familial subcortical stroke. The genetics and phenotypes of monogenic stroke are covered in this review. However, the majority of cases of ischaemic stroke are multifactorial in… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 161 extracted citations


Publications referenced by this paper.
Showing 1-10 of 241 references

Similar Papers

Loading similar papers…