Genetics and ischaemic stroke.

@article{Hassan2000GeneticsAI,
  title={Genetics and ischaemic stroke.},
  author={Ahamad Hassan and Hugh S. Markus},
  journal={Brain : a journal of neurology},
  year={2000},
  volume={123 ( Pt 9)},
  pages={1784-812}
}
Ischaemic stroke can be caused by a number of monogenic disorders, and in such cases stroke is frequently part of a multisystem disorder. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL), due to mutations in the NOTCH: 3 gene, is increasingly appreciated as a cause of familial subcortical stroke. The genetics and phenotypes of monogenic stroke are covered in this review. However, the majority of cases of ischaemic stroke are multifactorial in… CONTINUE READING

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