Genetics and genomics of ischemic tolerance: focus on cardiac and cerebral ischemic preconditioning.

Abstract

A subthreshold ischemic insult applied to an organ such as the heart and/or brain may help to reduce damage caused by subsequent ischemic episodes. This phenomenon is known as ischemic tolerance mediated by ischemic preconditioning (IPC) and represents the most powerful endogenous mechanism against ischemic injury. Various molecular pathways have been… (More)
DOI: 10.2217/pgs.12.157

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Cite this paper

@article{DellaMorte2012GeneticsAG, title={Genetics and genomics of ischemic tolerance: focus on cardiac and cerebral ischemic preconditioning.}, author={David Della-Morte and Fiorella Guadagni and Raffaele Palmirotta and Patrizia Ferroni and Gianluca Testa and Francesco Cacciatore and Pasquale Abete and F. Rengo and Miguel A. P{\'e}rez-Pinz{\'o}n and Ralph L. Sacco and Tatjana Rundek}, journal={Pharmacogenomics}, year={2012}, volume={13 15}, pages={1741-57} }