Genetics and genomics of asthma and allergic diseases.

  title={Genetics and genomics of asthma and allergic diseases.},
  author={William O C M Cookson},
  journal={Immunological reviews},
Asthma and eczema (atopic dermatitis) are characterized by a number of unexplained phenomena: the familial aggregation of disease, the initiation of disease by apparently trivial exposure to allergens, the preferential transmission of disease from affected mothers and the large increase in prevalence of disease in Westernized societies in the last century. A number of genes and chromosomal regions have been identified that consistently show linkage to asthma and its related phenotypes. Known… CONTINUE READING