Genetics and genetic testing in hemolytic uremic syndrome/thrombotic thrombocytopenic purpura.

@article{Noris2010GeneticsAG,
  title={Genetics and genetic testing in hemolytic uremic syndrome/thrombotic thrombocytopenic purpura.},
  author={Marina Noris and Giuseppe Remuzzi},
  journal={Seminars in nephrology},
  year={2010},
  volume={30 4},
  pages={395-408}
}
The hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are rare diseases that manifest with thrombocytopenia and microangiopathic hemolytic anemia accompanied by renal and neurologic dysfunction. Most childhood cases of HUS are caused by Shiga-toxin-producing bacteria and have a good prognosis. The other form, atypical HUS (aHUS… CONTINUE READING