Genetics and Parkinson's disease.

  title={Genetics and Parkinson's disease.},
  author={Dennis John Cordato and Daniel Kam Yin Chan},
  journal={Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia},
  volume={11 2},
Idiopathic Parkinson's disease is a neurodegenerative disorder that affects 1-2% of the population over the age of 65 years. Its aetiology is most likely a combination of complex genetic and environmental factors. Although Mendelian inheritance is seen in less than 5% of cases, recent studies have identified three genes mutations causing Parkinson's disease with a Mendelian inheritance pattern: autosomal dominantly inherited mutations of the alpha-synuclein gene on chromosome 4q21-q23… CONTINUE READING
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