Genetics, genomics, and cancer risk assessment: State of the Art and Future Directions in the Era of Personalized Medicine.

@article{Weitzel2011GeneticsGA,
  title={Genetics, genomics, and cancer risk assessment: State of the Art and Future Directions in the Era of Personalized Medicine.},
  author={Jeffrey N. Weitzel and Kathleen Reilly Blazer and Deborah J Macdonald and Julie O. Culver and Kenneth Offit},
  journal={CA: a cancer journal for clinicians},
  year={2011},
  volume={61 5},
  pages={
          327-59
        }
}
Scientific and technologic advances are revolutionizing our approach to genetic cancer risk assessment, cancer screening and prevention, and targeted therapy, fulfilling the promise of personalized medicine. In this monograph, we review the evolution of scientific discovery in cancer genetics and genomics, and describe current approaches, benefits, and barriers to the translation of this information to the practice of preventive medicine. Summaries of known hereditary cancer syndromes and… CONTINUE READING
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