Genetics, Receptor Binding, Replication, and Mammalian Transmission of H4 Avian Influenza Viruses Isolated from Live Poultry Markets in China

@inproceedings{Liang2016GeneticsRB,
  title={Genetics, Receptor Binding, Replication, and Mammalian Transmission of H4 Avian Influenza Viruses Isolated from Live Poultry Markets in China},
  author={Libin Liang and Guohua Deng and Jianzhong Shi and Shuai Wang and Qianyi Zhang and Huihui Kong and Chunyang Gu and Yuntao Guan and Yasuo Suzuki and Yanbing Li and Yongping Jiang and Guobin Tian and Liling Liu and Chengjun Li and Hualan Chen and Terence S Dermody},
  booktitle={Journal of virology},
  year={2016}
}
UNLABELLED H4 avian influenza virus (AIV) is one of the most prevalent influenza virus subtypes in the world. However, whether H4 AIVs pose a threat to public health remains largely unclear. Here, we analyzed the phylogenetic relationships, receptor binding properties, replication, and transmissibility in mammals of H4 AIVs isolated from live poultry markets in China between 2009 and 2012. Genomic sequence analysis of 36 representative H4 viruses revealed 32 different genotypes, indicating that… CONTINUE READING
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