Genetically informative research on adolescent substance use: methods, findings, and challenges.

@article{Lynskey2010GeneticallyIR,
  title={Genetically informative research on adolescent substance use: methods, findings, and challenges.},
  author={Michael T Lynskey and Arpana Agrawal and A Christopher Heath},
  journal={Journal of the American Academy of Child and Adolescent Psychiatry},
  year={2010},
  volume={49 12},
  pages={1202-14}
}
OBJECTIVE To provide an overview of the genetic epidemiology of substance use and misuse in adolescents. METHOD A selective review of genetically informative research strategies, their limitations, and key findings examining issues related to the heritability of substance use and substance use disorders in children and adolescents is presented. RESULTS Adoption, twin, and extended-family designs have established there is a strong heritable component to liability to nicotine, alcohol, and… CONTINUE READING