Genetically determined resistance to infection with group B arboviruses. I. Distribution of the resistance gene among various mouse populations and characteristics of gene expression in vivo.

@article{Darnell1974GeneticallyDR,
  title={Genetically determined resistance to infection with group B arboviruses. I. Distribution of the resistance gene among various mouse populations and characteristics of gene expression in vivo.},
  author={Margo B. Darnell and Hilary Prof Koprowski and Kari Y. H. Lagerspetz},
  journal={The Journal of infectious diseases},
  year={1974},
  volume={129 3},
  pages={
          240-7
        }
}
Resistance to group B arbovirus infection is inherited in mice as a dominant, autosomal allele. The BRVR, PRI, and C3H/RV inbred strains of mice are homozygous for this resistance. In the present study numerous other inbred strains of laboratory mice and wild Mus musculus were tested. No other inbred strain was able to resist infection with group B arboviruses; however, wild mice obtained from widely separated geographical areas were resistant to the infection. Breeding studies with one… 
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