Genetically determined differences in liver alcohol dehydrogenase activity in male rats

Abstract

Alcohol dehydrogenase (EC 1.1.1.1) activity was measured in liver extracts from one outbred and three inbred strains of rats. Strain-specific differences in enzyme activity were observed in the adult male rats. The differences appeared as the animals reached puberty. Studies on the enzyme purified from Sprague-Dawley and ACI rats indicate that the enzymes… (More)
DOI: 10.1007/BF00499942

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