Genetically dependent modulation of serotonergic inactivation in the human prefrontal cortex

@article{Passamonti2008GeneticallyDM,
  title={Genetically dependent modulation of serotonergic inactivation in the human prefrontal cortex},
  author={Luca Passamonti and Antonio Cerasa and Maria C. Gioia and Angela Magariello and Maria Muglia and Aldo Quattrone and Francesco Fera},
  journal={NeuroImage},
  year={2008},
  volume={40},
  pages={1264-1273}
}
Previous research suggests that genetic variations regulating serotonergic neurotransmission mediate individual differences in the neural network underlying impulsive and aggressive behaviour. Although with conflicting findings, the monoamine oxidase-A (MAOA) and the serotonin transporter (5HTT) gene polymorphisms have been associated with an increased risk to develop impulsive and aggressive behaviour. Double knock-out mice studies have also demonstrated that MAOA and 5HTT genes strongly… CONTINUE READING

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