Genetic variations and haplotypes in TIM-3 gene and the risk of gastric cancer

@article{Cao2010GeneticVA,
  title={Genetic variations and haplotypes in TIM-3 gene and the risk of gastric cancer},
  author={Bangwei Cao and Linzhong Zhu and Shengtao Zhu and Danping Li and Chuanzhen Zhang and Changqing Xu and Shutian Zhang},
  journal={Cancer Immunology, Immunotherapy},
  year={2010},
  volume={59},
  pages={1851-1857}
}
T cell immunoglobulin and mucin domain-containing molecule 3 (TIM-3) could weaken the Th1-mediated anti-tumor responses and accelerate the tumor cell proliferation by inhabiting the production of IL-2 or IFN-γ. This study was to assess the association between TIM-3 genetic variations and the development of gastric cancer. Five polymorphisms located in the promoter or encoding region of TIM-3 gene were genotyped in 212 gastric cancer patients and 252 controls who matched with the patients on the… CONTINUE READING
14 Citations
22 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 22 references

Similar Papers

Loading similar papers…