Genetic variation within TLR10 is associated with Crohn's disease in a New Zealand population.

Abstract

Toll-like receptors (TLRs) play an important role in the induction and regulation of the innate immune system and have been implicated in both infectious and inflammatory diseases. Recently the first association of TLR10 with Crohn's disease (CD) was reported. Here, we attempted to validate this association, using a candidate gene single nucleotide… (More)
DOI: 10.1016/j.humimm.2012.01.015

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