Genetic variation of the androgen receptor and risk of myocardial infarction and ischemic stroke in women.

@article{Rexrode2008GeneticVO,
  title={Genetic variation of the androgen receptor and risk of myocardial infarction and ischemic stroke in women.},
  author={Kathryn M. Rexrode and Paul M. Ridker and Hillary H Hegener and Julie E. Buring and Joann E. Manson and Robert Y L Zee},
  journal={Stroke},
  year={2008},
  volume={39 5},
  pages={
          1590-2
        }
}
BACKGROUND AND PURPOSE Androgen receptors (AR) are expressed in endothelial cells and vascular smooth-muscle cells. Some studies suggest an association between AR gene variation and risk of cardiovascular disease (CVD) in men; however, the relationship has not been examined in women. METHODS Six haplotype block-tagging single nucleotide polymorphisms (rs962458, rs6152, rs1204038, rs2361634, rs1337080, rs1337082), as well as the cysteine, adenine, guanine (CAG) microsatellite in exon 1, of the… CONTINUE READING

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