Genetic variation of miRNA sequence in pancreatic cancer.

  title={Genetic variation of miRNA sequence in pancreatic cancer.},
  author={Zheng-ming Zhu and Wentao Gao and Zhuyin Qian and Yi Miao},
  journal={Acta biochimica et biophysica Sinica},
  volume={41 5},
MicroRNAs (miRNAs) are small non-coding RNAs of 20-22 nucleotides (nts) and constitute a novel class of gene regulators that negatively regulate gene expression at the post-transcriptional level. The expression of miRNA is deregulated in many types of cancers. Alterations in miRNA expression may be an important contributor to the development of pancreatic… CONTINUE READING