Genetic variation in transmission success of the Lyme borreliosis pathogen Borrelia afzelii.

@article{Tonetti2015GeneticVI,
  title={Genetic variation in transmission success of the Lyme borreliosis pathogen Borrelia afzelii.},
  author={Nicolas Tonetti and Maarten J Voordouw and Jonas Durand and S{\'e}verine Monnier and L. E. Gern},
  journal={Ticks and tick-borne diseases},
  year={2015},
  volume={6 3},
  pages={334-43}
}
The vector-to-host and host-to-vector transmission steps are the two critical events that define the life cycle of any vector-borne pathogen. We expect negative genetic correlations between these two transmission phenotypes, if parasite genotypes specialized at invading the vector are less effective at infecting the vertebrate host and vice versa. We used the tick-borne bacterium Borrelia afzelii, a causative agent of Lyme borreliosis in Europe, to test whether genetic trade-offs exist between… CONTINUE READING
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