Genetic variation in the toll-like receptor 4 and prostate cancer incidence and mortality.


BACKGROUND Common genetic variants in the Toll-like receptor 4 (TLR4), which is involved in inflammation and immune response pathways, may be important for prostate cancer. METHODS In a large nested case-control study of prostate cancer in the Physicians' Health Study (1982-2004), 10 single nucleotide polymorphisms (SNPs) were selected and genotyped to… (More)
DOI: 10.1002/pros.21423