Genetic variation in the interleukin-10 gene promoter in Polish patients with systemic lupus erythematosus

Abstract

Identification of susceptibility genes in systemic lupus erythematosus (SLE) has recently become a topic of interest. The IL-10 promoter contains three single base-pair substitutions at −627C > A, −854C > T and −1117G > A. These single base-pair substitutions produce three different haplotypes, GCC, ACC and ATA, which affect IL-10 expression. We examined… (More)
DOI: 10.1007/s00296-008-0776-4

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@article{Sobkowiak2008GeneticVI, title={Genetic variation in the interleukin-10 gene promoter in Polish patients with systemic lupus erythematosus}, author={Adam Sobkowiak and Margarita Lianeri and Mariusz Wudarski and Jan Krzysztof Łącki and Paweł P Jagodziński}, journal={Rheumatology International}, year={2008}, volume={29}, pages={921-925} }