Genetic variation in the G72 (DAOA) gene affects temporal lobe and amygdala structure in subjects affected by bipolar disorder.

@article{Zuliani2009GeneticVI,
  title={Genetic variation in the G72 (DAOA) gene affects temporal lobe and amygdala structure in subjects affected by bipolar disorder.},
  author={Riccardo Zuliani and T. William J. Moorhead and Dominic Edward Job and James W McKirdy and Jessika E D Sussmann and Eve C. Johnstone and Stephen M Lawrie and Paolo Brambilla and Jeremy Hall and Andrew M. McIntosh},
  journal={Bipolar disorders},
  year={2009},
  volume={11 6},
  pages={621-7}
}
BACKGROUND Variation in the G72 (DAOA) gene is understood to convey susceptibility for bipolar disorder through an uncertain mechanism. Little is known about the structural brain phenotypes associated with this gene. We hypothesised that reductions in temporal lobe and amygdala gray matter would be associated with variation at two loci in the gene for which evidence of genetic linkage has been repeatedly demonstrated. METHODS We examined the temporal lobe and amygdala gray matter associations… CONTINUE READING