Genetic variation in the 5-HT5A receptor gene in patients with bipolar disorder and major depression

@article{Arias2001GeneticVI,
  title={Genetic variation in the 5-HT5A receptor gene in patients with bipolar disorder and major depression},
  author={B{\'a}rbara Arias and David A. Collier and Crist{\'o}bal Gast{\'o} and Luis Pintor and Lourdes Fa{\~n}an{\'a}s},
  journal={Neuroscience Letters},
  year={2001},
  volume={303},
  pages={111-114}
}
In the present study, genetic variation of the 5-HT5A receptor was analyzed in patients affected by affective disorders and healthy controls. The sample consisted of 181 patients with major depression, 88 patients with bipolar affective disorder (BP) and 157 unrelated controls (C), all of Spanish origin. Two polymorphisms (-19G/C and 12A/T) in the 5-HT5A receptor gene were analyzed by polymerase chain reaction amplification and subsequent enzyme digestion. No genotype, allele or haplotype… CONTINUE READING

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