Genetic variation in platinating agent and taxane pathway genes as predictors of outcome and toxicity in advanced non-small-cell lung cancer.

@article{Lamba2014GeneticVI,
  title={Genetic variation in platinating agent and taxane pathway genes as predictors of outcome and toxicity in advanced non-small-cell lung cancer.},
  author={Jatinder Lamba and Brooke L. Fridley and Taraswi M. Ghosh and Qing Yu and Gaurav A. Mehta and Pankaj Gupta},
  journal={Pharmacogenomics},
  year={2014},
  volume={15 12},
  pages={1565-74}
}
AIM Lung carcinoma is the most common malignancy and the leading cause of cancer deaths worldwide. Although clinical factors including age, performance status and stage influence the likelihood of benefit from and tolerability of chemotherapy, the genetic profile of individual patients may be an independent predictor of response and toxicity. The present… CONTINUE READING