Genetic variation in coagulation and fibrinolytic proteins and their relation with acute myocardial infarction: a systematic review.

@article{Boekholdt2001GeneticVI,
  title={Genetic variation in coagulation and fibrinolytic proteins and their relation with acute myocardial infarction: a systematic review.},
  author={S. Matthijs Boekholdt and Nick R. Bijsterveld and Arno H M Moons and Marcel M. Levi and Harry Roger B{\"u}ller and Ron J. G. Peters},
  journal={Circulation},
  year={2001},
  volume={104 25},
  pages={3063-8}
}
BACKGROUND It is pathophysiologically conceivable that genetic variations in coagulation and fibrinolytic proteins are associated with the risk of myocardial infarction. Methods and Results- We performed a literature search to identify published case-control studies correlating the factor V Leiden or prothrombin G20210A mutations or fibrinogen G-455A or plasminogen activator inhibitor-1 (PAI-1) 4G/5G polymorphisms with the risk of myocardial infarction. Studies were included only if they used… CONTINUE READING

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