Genetic variation in bone-regenerative capacity among inbred strains of mice.

@article{Li2001GeneticVI,
  title={Genetic variation in bone-regenerative capacity among inbred strains of mice.},
  author={Xinmin Li and W Gu and Godfred L. Masinde and Melanie Hamilton-Ulland and Charles H. Rundle and Subburaman Mohan and David J. Baylink},
  journal={Bone},
  year={2001},
  volume={29 2},
  pages={134-40}
}
Genetic variation in bone-regenerative capacity has not been studied in any animal model system. We developed a "drill-hole" model in the tail vertebra of inbred strains of mice that allows us to reproducibly introduce an injury with a defined boundary and quantify the rate of bone healing using the combination of high-resolution Faxitron X-ray imaging and the ChemiImager 4000 Low Light Imaging System. Using this model, we demonstrate that bone-regenerative capacity is a genetically controlled… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

Inbred Strain-Specific Response to Biglycan Deficiency in the Cortical Bone of C57BL6/129 and C3H/He Mice

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research • 2009

Similar Papers

Loading similar papers…