Genetic variation in a human odorant receptor alters odour perception

@article{Keller2007GeneticVI,
  title={Genetic variation in a human odorant receptor alters odour perception},
  author={Andreas Keller and Hanyi Zhuang and Qiuyi Chi and Leslie B. Vosshall and Hiroaki Matsunami},
  journal={Nature},
  year={2007},
  volume={449},
  pages={468-472}
}
Human olfactory perception differs enormously between individuals, with large reported perceptual variations in the intensity and pleasantness of a given odour. For instance, androstenone (5α-androst-16-en-3-one), an odorous steroid derived from testosterone, is variously perceived by different individuals as offensive (“sweaty, urinous”), pleasant (“sweet, floral”) or odourless. Similar variation in odour perception has been observed for several other odours. The mechanistic basis of variation… Expand
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