Genetic variation in RNASEL and risk for prostate cancer in a population-based case-control study.

Abstract

BACKGROUND Linkage studies have implicated chromosome 1q24 as a putative locus for hereditary prostate cancer. The RNASEL gene maps to 1q24 and has been associated with prostate cancer risk in multiple family-based linkage studies. The RNASEL gene product combats viral infection by degrading viral RNA and inducing apoptosis of infected cells. Few studies… (More)
DOI: 10.1002/pros.21370

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