• DOI:10.1038/nature08309
Corpus ID: 1707096

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

@article{Ge2009GeneticVI,
  title={Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance},
  author={D. Ge and J. Fellay and A. Thompson and J. Simon and K. Shianna and T. Urban and E. Heinzen and P. Qiu and A. Bertelsen and A. Muir and M. Sulkowski and J. McHutchison and D. Goldstein},
  journal={Nature},
  year={2009},
  volume={461},
  pages={399-401}
}

D. Ge, J. Fellay, +10 authors D. Goldstein

Published 2009

Medicine, Biology

Nature

Chronic infection with hepatitis C virus (HCV) affects 170 million people worldwide and is the leading cause of cirrhosis in North America. Although the recommended treatment for chronic infection involves a 48-week course of peginterferon-α-2b (PegIFN-α-2b) or -α-2a (PegIFN-α-2a) combined with ribavirin (RBV), it is well known that many patients will not be cured by treatment, and that patients of European ancestry have a significantly higher probability of being cured than patients of African… CONTINUE READING

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