Genetic variation and gene expression in antioxidant related enzymes and risk of COPD: a systematic review.

@article{Bentley2008GeneticVA,
  title={Genetic variation and gene expression in antioxidant related enzymes and risk of COPD: a systematic review.},
  author={Amy R. Bentley and Parastu S Emrani and Patricia A Cassano},
  journal={Thorax},
  year={2008},
  volume={63 11},
  pages={956-61}
}
BACKGROUND Observational epidemiological studies of dietary antioxidant intake, serum antioxidant concentration and lung outcomes suggest that lower levels of antioxidant defences are associated with decreased lung function. Another approach to understanding the role of oxidant/antioxidant imbalance in the risk of chronic obstructive pulmonary disease (COPD) is to investigate the role of genetic variation in antioxidant enzymes, and indeed family based studies suggest a heritable component to… CONTINUE READING

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