Genetic variants in the renin-angiotensin-aldosterone system and blood pressure responses to potassium intake.

@article{He2011GeneticVI,
  title={Genetic variants in the renin-angiotensin-aldosterone system and blood pressure responses to potassium intake.},
  author={Jiang He and Dongfeng Gu and Tanika N. Kelly and James E. Hixson and D. Chandrasekhra Rao and Cashell E. Jaquish and Jing Chen and Qi Zhao and Chi Charles Gu and Jianfeng Huang and Lawrence C. Shimmin and Ji-chun Chen and Jianjun Mu and Xu Yin Ji and De-Pei Liu and Paul Kieran Whelton},
  journal={Journal of hypertension},
  year={2011},
  volume={29 9},
  pages={1719-30}
}
OBJECTIVE Observational epidemiologic studies and clinical trials have documented that dietary potassium intake lowers blood pressure (BP). We examined the association between genetic variants in the renin-angiotensin-aldosterone system and BP responses to potassium intervention. METHODS A 7-day high-sodium followed by a 7-day high-sodium plus 60 mmol/day potassium-supplementation feeding study was conducted among 1906 participants from rural northern China. Nine BP measurements were obtained… CONTINUE READING