Genetic variants in the UCP2-UCP3 gene cluster and risk of diabetes in the Women's Health Initiative Observational Study.

@article{Hsu2008GeneticVI,
  title={Genetic variants in the UCP2-UCP3 gene cluster and risk of diabetes in the Women's Health Initiative Observational Study.},
  author={Y H Hsu and Tianhua Niu and Yiqing Song and Lesley T Tinker and Lewis H. Kuller and Simin Liu},
  journal={Diabetes},
  year={2008},
  volume={57 4},
  pages={1101-7}
}
OBJECTIVE Mitochondrial uncoupling proteins (UCPs) are involved in body weight regulation and glucose homeostasis. Genetic variants in the UCP2-UCP3 gene cluster, located on chromosome 11q13, may play a significant role in the development of type 2 diabetes. RESEARCH DESIGN AND METHODS We conducted a comprehensive assessment of common single nucleotide… CONTINUE READING