Genetic variants in immunoregulatory genes and risk for childhood lymphomas.

  title={Genetic variants in immunoregulatory genes and risk for childhood lymphomas.},
  author={Elisabeth K. Andrie and A Michos and Vassiliki Kalampoki and Apostolos Pourtsidis and Maria A. Moschovi and Sophia Polychronopoulou and Fani Athanasiadou-Piperopoulou and Maria C Kalmanti and Angelos Hatzakis and Dimitrios Paraskevis and Alexandra Nieters and Eleni Th Petridou},
  journal={European journal of haematology},
  volume={83 4},
To investigate whether single nucleotide polymorphisms (SNPs) in key cytokine and innate immunity genes influence risk for childhood lymphomas, we genotyped 37 children with Hodgkin's (HL) and 48 with non-Hodgkin's lymphoma (NHL), aged (1 month-14 yr), along with their 85 age- and gender-matched controls suffering from mild medical conditions. Genotypic analysis was performed for 10 SNPs from nine genes with important role in immunoregulatory pathways (IL4, IL4R, IL6, IL10, IL12, IL18, TNFalpha… CONTINUE READING


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