Genetic variants in FGFR2 and MAP3K1 are associated with the risk of familial and early-onset breast cancer in a South-American population

Abstract

Genome-Wide Association Studies have identified several loci associated with breast cancer (BC) in populations of different ethnic origins. One of the strongest associations was found in the FGFR2 gene, and MAP3K1 has been proposed as a low-penetrance BC risk factor. In this study, we evaluated the associations among FGFR2 SNPs rs2981582, rs2420946, and… (More)
DOI: 10.1007/s10549-012-2359-z

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@article{Jara2012GeneticVI, title={Genetic variants in FGFR2 and MAP3K1 are associated with the risk of familial and early-onset breast cancer in a South-American population}, author={Lilian Jara and Patricio Gonz{\'a}lez-Hormaz{\'a}bal and Kerube Cerce{\~n}o and Gabriella A. Di Capua and Jos{\'e} Miguel Reyes and Rafael Llombart Blanco and Teresa Bravo and Octavio Peralta and Fernando G{\'o}mez and Enrique Waugh and Sonia B. Margarit and Gladys Ibanez and C. R. Hern{\'a}ndez Romero and Janara Pakomio and Gigia Roizen}, journal={Breast Cancer Research and Treatment}, year={2012}, volume={137}, pages={559-569} }