Genetic variants at PSMD3 interact with dietary fat and carbohydrate to modulate insulin resistance.

PSMD3 encodes subunit 3 of the 26S proteasome, which is involved in regulating insulin signal transduction, and dietary factors could potentially regulate the function of this gene. We aimed to investigate the associations of PSMD3 variants with glucose-related traits and the interactions of those variants with dietary fat and carbohydrate for glucose… CONTINUE READING