Genetic variability in ABCB1, occupational pesticide exposure, and Parkinson's disease.

@article{Narayan2015GeneticVI,
  title={Genetic variability in ABCB1, occupational pesticide exposure, and Parkinson's disease.},
  author={Shilpa Narayan and Janet S. Sinsheimer and Kimberly C. Paul and Zeyan Liew and Myles G. Cockburn and Jeff M. Bronstein and Beate R. Ritz},
  journal={Environmental research},
  year={2015},
  volume={143 Pt A},
  pages={98-106}
}
BACKGROUND Studies suggested that variants in the ABCB1 gene encoding P-glycoprotein, a xenobiotic transporter, may increase susceptibility to pesticide exposures linked to Parkinson's Disease (PD) risk. OBJECTIVES To investigate the joint impact of two ABCB1 polymorphisms and pesticide exposures on PD risk. METHODS In a population-based case control… CONTINUE READING