Genetic tracing shows segregation of taste neuronal circuitries for bitter and sweet.

@article{Sugita2005GeneticTS,
  title={Genetic tracing shows segregation of taste neuronal circuitries for bitter and sweet.},
  author={Makoto Sugita and Yoshiki Shiba},
  journal={Science},
  year={2005},
  volume={309 5735},
  pages={781-5}
}
The recent discovery of mammalian bitter, sweet, and umami taste receptors indicates how the different taste qualities are encoded at the periphery. However, taste representations in the brain remain elusive. We used a genetic approach to visualize the neuronal circuitries of bitter and sweet tastes in mice to gain insight into how taste recognition is accomplished in the brain. By selectively expressing a transsynaptic tracer in either bitter- or sweet and/or umami-responsive taste receptor… CONTINUE READING

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